1. This point is closely related to the lesson "extending
a sentence with a semicolon" as it concerns merging two sentences to form one. However, in these examples, there is a short bridge between the first half and the second half. The bridge is known as a "transitional phrase". There is always a comma after a transitional phrase. (The transitional phrases are shown in bold below.)
Examples:
Everyone knows he is guilty;
of course, it will never be proved.
(The transitional phrase "of course" acts like a bridge between the first half and
the second half.)
Sarah's guest was turned away by the doorman;
as a result, she left before the presentations.
("as a result" - transitional phrase)
Business is booming;
for example, Siemens have made 10 orders since
4 o'clock. 
("for example" - transitional phrase)
I missed the early plane;
however, I still made the meeting.
("however" - transitional phrase)
The paper is stuck in the lift;
consequently, we cannot finish the printing.
("consequently" - transitional phrase)
She does not loathe chess,
on the contrary, she quite likes it. 
(The term "on the contrary" is a transitional phrase. You cannot merge two
sentences into one with a comma. You must either start a new sentence or
use a semicolon.)
My security guards are not trained in fire-fighting;
therefore, we paged the
fire service.
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DEFINITELY NOT A COMMA
Transitional phrases are common. Most of the time, a transitional phrase will start a new sentence. However, you can use a semicolon if you wish to bring it closer to the original sentence. You cannot do this with a comma. This is a very common mistake.
It is extremely foggy, nevertheless, the game will
be played. 
MAIN CULPRIT IS "HOWEVER"
The error described above is called a "comma fault". This error is most commonly seen with the word "however".
I am leaving on Tuesday, however, I will be back on Wednesday
to collect my wages. 
I am leaving on Tuesday; however, I will be back on Wednesday
to collect my wages.
I am leaving on Tuesday. However, I will be back on Wednesday
to collect my wages.
COMMA AFTER "SO"
When the word "so" is used to mean "therefore", it is a transitional phrase and should be
followed by a comma.
We are not in a position to fund the changes. So, the current
system will remain until at least April when it will be
reviewed again.
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