1. Expressions such as "yes", "no" and "indeed" are used as "interjections".
Interjections can be followed by a comma.
Examples:
Well, the rain has played its part in the outcome of this match.

Yes, she will apologise.

Absolutely, a fifth of all the students live in the village.
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MILDER WITH A COMMA
An interjection can also be followed by an exclamation mark, but this gives the interjection more impact. (Consider the difference between "No!" and "No,".)
USUALLY NOT IN BUSINESS WRITING
Interjections are usually only used when spoken words are being quoted. You should avoid them in business writing.
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